[Association of PARK 16 polymorphisms with Parkinson's disease in Han population of Suzhou area].

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[Association of PARK 16 polymorphisms with Parkinson's disease in Han population of Suzhou area].

Zhonghua yi xue za zhi - 1 Feb 2011

Li Dong-Hui, Wang Jin, Mao Cheng-Jie, Hu Wei-Dong, Xiao Li, Yang Ya-Ping, Qin Zheng-Hong, Liu Chun-Feng

Abstract excerpt

OBJECTIVE: To investigate whether there is an association of PARK 16 locus with Parkinson's disease (PD) in Han population of Suzhou area. METHODS: Polymerase chain reaction (PCR), sequencing analysis, allele-specific PCR mediated by pfu DNA polymerases and real-time PCR were employed to determine the genotype of each subject. The PARK16 representative SNP rs947211 was analyzed in 160 PD patients and 200...

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PMID: 21419001

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