Article
Mutation analysis of PARK2 in a Uyghur family with early-onset Parkinson's disease in Xinjiang, China.
Journal of the neurological sciences - 15 Jul 2014
Li Hongyan, Yusufujiang Aishanjiang, Naser Shaliya, Zhu Yi, Maimaiti Mayinur, He Xiaoyan, Bu Juan, Meng Xuegang, Wang Mingyuan, Li Jiang, Dina Baiting, Yang Lijuan, Nayi Zuhere, Dang Hui, Wang Chengfeng, Amiti Dilimulati, Aji Asiya, Yusufu Nazuke, Jiao Yan, Duan Fengmei
Abstract excerpt
BACKGROUND: The PARK2 gene was recently identified as a causative gene for autosomal recessive early-onset Parkinson's disease (EOPD). Studies on how specific PARK2 mutations are manifested on different genetic backgrounds may benefit prognosis and clinical management. Until now, there have been no reports of PARK2 mutations in a Uyghur family with EOPD. METHODS: We identified a large Uyghur EOPD family with...
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