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PARK2 gene mutations in early onset Parkinson's disease patients of South India.

Neuroscience letters - 15 Aug 2012

Padmaja M Vishwanathan, Jayaraman Meenakshi, Srinivasan Avathvadi Venkatesan, Srisailapathy C R Srikumari, Ramesh Arabandi

Abstract excerpt

With the etiology being unclear till date, a combination of age, genetic and environmental factors are known to play a significant role in the pathogenesis of Parkinson's disease. Mutations in PARK2 gene have been implicated to cause autosomal recessive early onset PD. We analyzed the 12 coding exons of PARK2 gene in 16 early onset PD patients of South Indian ethnicity. PARK2 mutations were present in 68% of the...

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PMID: 22766139
DOI: 10.1016/j.neulet.2012.06.062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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