Article
Molecular pathogenesis of Parkinson's disease: identification of mutations in the Parkin gene in Indian patients.
Parkinsonism & related disorders - 1 Oct 2006
Biswas Arindam, Gupta Arnab, Naiya Tufan, Das Gautami, Neogi Rajarshi, Datta Somnath, Mukherjee Subhas, Das Shyamal K, Ray Kunal, Ray Jharna
Abstract excerpt
Parkinson's disease (PD), the second most common neurodegenerative disorder, affects at least 1% of the population over the age of 50. However, very little information is available regarding the molecular basis of PD among Indians. Since the largest number of mutations have been detected in the Parkin gene among all known PD loci, we aim to use Parkin as the candidate gene to assess its role in PD-related...
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