Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Compartment-specific protection of iron-sulfur proteins by superoxide dismutase.

The Journal of biological chemistry - 28 Nov 2003

Missirlis Fanis, Hu Jianguo, Kirby Kim, Hilliker Arthur J, Rouault Tracey A, Phillips John P

Abstract excerpt

Iron and oxygen are essential but potentially toxic constituents of most organisms, and their transport is meticulously regulated both at the cellular and systemic levels. Compartmentalization may be a homeostatic mechanism for isolating these biological reactants in cells. To investigate this hypothesis, we have undertaken a genetic analysis of the interaction between iron and oxygen metabolism in Drosophila. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aconitate Hydratase
Share to Cytosol
Share to Herbicides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Iron-Sulfur Proteins

Share to Oxygen

Share to Paraquat

Share to Superoxide Dismutase-1

Share to Superoxides

Source

Identifiers

PMID: 12972424
DOI: 10.1074/jbc.M307700200

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Compartment-specific protection of iron-sulfur proteins by superoxide dismutase.PMID 12972424Read ↗

Different regulation of wild-type and mutant Cu,Zn superoxide dismutase localization in mammalian mitochondria.Semantic proximity Read ↗

Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging.Semantic proximity Read ↗

Superoxide inhibits 4Fe-4S cluster enzymes involved in amino acid biosynthesis. Cross-compartment protection by CuZn-superoxide dismutase.Semantic proximity Read ↗

The effects of mitochondrial iron homeostasis on cofactor specificity of superoxide dismutase 2.Semantic proximity Read ↗

Enhancing autophagy by redox regulation extends lifespan in DrosophilaSemantic proximity Read ↗

Acylation of Superoxide Dismutase 1 (SOD1) at K122 Governs SOD1-Mediated Inhibition of Mitochondrial Respiration.Semantic proximity Read ↗

SOD2, the principal scavenger of mitochondrial superoxide, is dispensable for embryogenesis and imaginal tissue development but essential for adult survival.Semantic proximity Read ↗

Reactive oxygen species act remotely to cause synapse loss in a Drosophila model of developmental mitochondrial encephalopathy.Semantic proximity Read ↗

Quantitative evaluation of the mitochondrial proteomes of Drosophila melanogaster adapted to extreme oxygen conditions.Semantic proximity Read ↗

Down-regulation of iron regulatory protein 1 activities and expression in superoxide dismutase 1 knock-out mice is not associated with alterations in iron metabolism.Semantic proximity Read ↗

Mitochondrial superoxide acts in the intestine to extend longevitySemantic proximity Read ↗

Genomic regions responsible for manganese superoxide dismutase regulation in Drosophila melanogaster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.