Article
Genomic regions responsible for manganese superoxide dismutase regulation in Drosophila melanogaster.
Aging cell - 1 Aug 2003
Paul Anirban, Duttaroy Atanu
Abstract excerpt
The transcription of manganese superoxide dismutase (MnSOD), expression of which is essential for detoxification of superoxide radicals from mitochondria, has been shown to be regulated in vitro by many factors and conditions including oxidative stress, cytokines, lipopolysaccharide, cytoplasmic myc (c-myc), p53 and tumour necrosis factors. Here we describe genomic regions in Drosophila melanogaster with...
Topics
- Animals
- Down-Regulation
- Drosophila melanogaster
- Drug Tolerance
- Free Radicals
- Gene Deletion
- Gene Expression Regulation, Enzymologic
- Genes, Regulator
- Genome
- Mutation
- Paraquat
- RNA, Messenger