Association of katG, inhA, and AhpC Mutations with Isoniazid Resistance of Mycobacterium tuberculosis in Pulmonary Tuberculosis Patients from Nanjing, China.

doi:10.1177/10766294261446052

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Article

Association of katG, inhA, and AhpC Mutations with Isoniazid Resistance of Mycobacterium tuberculosis in Pulmonary Tuberculosis Patients from Nanjing, China.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jul 2026

Yang Yan, Liu Yi, Huang Yan, Niu Yulan, Kong Jun, Zhang Xiangrong

Abstract excerpt

The drug-resistant profile of tuberculosis (TB) varies across geological regions. This study aimed to evaluate the association of katG, inhA, and AhpC mutations with isoniazid (INH) resistance of Mycobacterium tuberculosis in pulmonary TB patients from Nanjing, China. Laboratory and genetic data of INH-resistant genes in TB patients living in Nanjing and hospitalized in the Department of Tuberculosis, the Second...

Topics

Humans
Mycobacterium tuberculosis
Isoniazid
Antitubercular Agents
China
Tuberculosis, Pulmonary
Mutation
Catalase
Bacterial Proteins
Female
Microbial Sensitivity Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oxidoreductases

Male

Promoter Regions, Genetic

Adult

Tuberculosis, Multidrug-Resistant

Middle Aged

Retrospective Studies

Source

Open in PubMed

Identifiers

PMID: 42037600
DOI: 10.1177/10766294261446052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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