Article
Toll-like receptor 8 polymorphism and coronary artery disease.
Molecular biology reports - 1 Sept 2009
Chen Zhong, Ma Genshan, Qian Qi, Yao Yuyu, Feng Yi, Tang Chengchun
Abstract excerpt
Toll-like receptors (TLRs) play roles in innate and adaptive immune responses. Some TLRs are involved in the pathogenesis of cardiovascular diseases. Coronary artery disease (CAD) has an inflammatory and immunological basis. We investigated whether TLR8 Met1Val and TLR8-129G>C single nucleotide polymorphisms (SNPs rs3764879 and rs3764880) are associated with CAD in the Chinese population. We enrolled 412...
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