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Article

Genetics supersedes epigenetics in colon cancer phenotype.

Cancer cell - 1 Aug 2003

Yamashita Kentaro, Dai Tomoko, Dai Yuichi, Yamamoto Fumiichiro, Perucho Manuel

Abstract excerpt

A CpG island DNA methylator phenotype has been postulated to explain silencing of the hMLH1 DNA mismatch repair gene in cancer of the microsatellite mutator phenotype. To evaluate this model, we analyzed methylation in CpG islands from six mutator and suppressor genes, and thirty random genomic s...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12957287
DOI: 10.1016/s1535-6108(03)00190-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12957287-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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