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Article

Rapid and large-scale formation of chondrocyte aggregates by rotational culture.

Cell transplantation - 1 Jan 2003

Furukawa Katsuko S, Suenaga Hideyuki, Toita Kenshi, Numata Akiko, Tanaka Junzo, Ushida Takashi, Sakai Yasuyuki, Tateishi Tetsuya

Abstract excerpt

Chondrocytes in articular cartilage synthesize collagen type II and large sulfated proteoglycans, whereas the same cells cultured in monolayer (2D) dedifferentiate into fibroblastic cells and express collagen type I and small proteoglycans. On the other hand, a pellet culture system was developed as a method for preventing the phenotypic modulation of chondrocytes and promoting the redifferentiation of...

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Identifiers

PMID: 12953921
DOI: 10.3727/000000003108747037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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