Article
Functional tissue-engineered microtissue derived from cartilage extracellular matrix for articular cartilage regeneration.
Acta biomaterialia - 1 Sept 2018
Yin Heyong, Wang Yu, Sun Xun, Cui Ganghua, Sun Zhen, Chen Peng, Xu Yichi, Yuan Xueling, Meng Haoye, Xu Wenjing, Wang Aiyuan, Guo Quanyi, Lu Shibi, Peng Jiang
Abstract excerpt
We developed a promising cell carrier prepared from articular cartilage slices, designated cartilage extracellular matrix (ECM)-derived particles (CEDPs), through processes involving physical pulverization, size screening, and chemical decellularization. Rabbit articular chondrocytes (ACs) or adipose-derived stem cells (ASCs) rapidly attached to the surface of the CEDPs and proliferated with high cell viability...
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