Article
Chondrocyte aggregation in suspension culture is GFOGER-GPP- and beta1 integrin-dependent.
The Journal of biological chemistry - 14 Nov 2008
Gigout Anne, Jolicoeur Mario, Nelea Monica, Raynal Nicolas, Farndale Richard, Buschmann Michael D
Abstract excerpt
Isolated chondrocytes form aggregates in suspension culture that maintain chondrocyte phenotype in a physiological pericellular environment. The molecular mechanisms involved in chondrocyte aggregation have not been previously identified. Using this novel suspension culture system, we performed mRNA and protein expression analysis along with immunohistochemistry for potential cell adhesion molecules and...
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