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Article

Human chondrocytes proliferate and produce matrix components in microcarrier suspension culture.

Biomaterials - 1 May 1996

Frondoza C, Sohrabi A, Hungerford D

Abstract excerpt

Chondrocytes propagated in monolayer culture proliferate and change into 'fibroblastoid'-like cells. This change is characterized by a shift in production of collagen type II to I and from high- to low-molecular-weight proteoglycans. When propagated in three-dimensional culture, chondrocytes have limited ability to divide but re-express their original characteristics. The goal of the present study was to...

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Identifiers

PMID: 8718933
DOI: 10.1016/0142-9612(96)83283-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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