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Article

The current situation with regard to human melanoma and genetic inferences.

Current opinion in oncology - 1 Mar 1996

Hayward N K

Abstract excerpt

A melanoma predisposition gene has been identified. This gene, CDKN2, maps to chromosome 9p21-p22 and encodes p16, an inhibitor of cyclin-dependent kinases 4 and 6. CDKN2 has been found to be inactivated by homozygous deletion or intragenic mutation at high frequency in a diverse range of tumors and tumor cell lines, including those derived from melanomas. Now a number of CDKN2 mutations have been found in the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8727306
DOI: 10.1097/00001622-199603000-00011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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