Molecular genetics of familial cutaneous melanoma.

doi:10.1200/JCO.1998.16.2.670

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Article

Molecular genetics of familial cutaneous melanoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Feb 1998

Haluska F G, Hodi F S

Abstract excerpt

PURPOSE: A family history of melanoma is a significant risk factor for the disease, and recently several loci that determine susceptibility to the development of melanoma have been identified. The most important of these is p16/CDKN2A. We attempted to determine the degree to which the p16/CDKN2A...

Topics

Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 9
Cyclin-Dependent Kinases
Genes, p16
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Germ-Line Mutation
Humans
Melanoma
Skin Neoplasms

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