Article
[Genetic counseling and DNA testing in patients with increased risks for malignant melanoma].
Therapeutische Umschau. Revue therapeutique - 1 Aug 2003
Itin P H, Fistarol S K
Abstract excerpt
There are numerous risk factors for the development of malignant melanoma. It has been documented that genetic predisposition exists but exogenous factors are also very important. In familial melanomas it has been well established that mutation in the CDKN2A gene which is located at chromosome 9 leads to a marked risk for malignant melanoma. This tumor-suppressor gene is important for the regulation of the cell...
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