Article
Phenocopies in melanoma-prone families with germ-line CDKN2A mutations.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Sept 2018
Helgadottir Hildur, Olsson Håkan, Tucker Margaret A, Yang Xiaohong R, Höiom Veronica, Goldstein Alisa M
Abstract excerpt
PURPOSE: Carriers of CDKN2A mutations have high risks of melanoma and certain other cancers. In this study we examined the occurrence of tumors among CDKN2A wild type (wt) members of melanoma-prone families with CDKN2A mutations. METHODS: Swedish and US melanoma-prone families with CDKN2A mutations were included. Data was collected on tumors diagnosed among family members. Among the CDKN2A mutated families,...
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