Article
Genome-wide RNAi analysis of growth and viability in Drosophila cells.
Science (New York, N.Y.) - 6 Feb 2004
Boutros Michael, Kiger Amy A, Armknecht Susan, Kerr Kim, Hild Marc, Koch Britta, Haas Stefan A, Paro Renato, Perrimon Norbert
Abstract excerpt
A crucial aim upon completion of whole genome sequences is the functional analysis of all predicted genes. We have applied a high-throughput RNA-interference (RNAi) screen of 19,470 double-stranded (ds) RNAs in cultured cells to characterize the function of nearly all (91%) predicted Drosophila g...
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