Article
Molecular mechanisms associated with the regulation of apoptosis by the two alternatively spliced products of c-Myb.
Molecular and cellular biology - 1 Sept 2003
Kumar Atul, Baker Stacey J, Lee Clement M, Reddy E Premkumar
Abstract excerpt
The c-myb proto-oncogene encodes two alternatively spliced mRNAs, which in turn code for proteins of 75 kDa and 89 kDa. It is at present unclear whether the two isoforms of c-Myb perform identical functions or whether they mediate different biological effects. To assess their role in apoptotic de...
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