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Article

c-Maf Induces Monocytic Differentiation and Apoptosis in Bipotent Myeloid Progenitors

1 Sept 1999

Abstract excerpt

The transcriptional mechanisms that drive colony-forming unit granulocyte-macrophage (CFU-GM) myeloid progenitors to differentiate into cells of either the granulocytic or monocytic lineage are not fully understood. We have shown that the c-Maf and c-Myb transcription factors physically interact in myeloid cells to form inhibitory complexes that hinder transactivation of c-Myb target genes through direct binding...

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Identifiers

PMID: 10477683
DOI: 10.1182/blood.v94.5.1578.417k18_1578_1589

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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