Article

c-Maf Induces Monocytic Differentiation and Apoptosis in Bipotent Myeloid Progenitors

1999-09-01

Abstract excerpt

Abstract The transcriptional mechanisms that drive colony-forming unit granulocyte-macrophage (CFU-GM) myeloid progenitors to differentiate into cells of either the granulocytic or monocytic lineage are not fully understood. We have shown that the c-Maf and c-Myb transcription factors physically interact in myeloid cells to form inhibitory complexes that hinder transactivation of c-Myb target genes through direct...

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Literature Corpus work: aa9f6de5-b5c3-5fd2-8855-edae7555d97c
DOI: 10.1182/blood.v94.5.1578

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