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Article

Phenotypic changes in MCF-7 cells during prolonged exposure to tamoxifen.

Molecular and cellular endocrinology - 29 Aug 2003

Fasco Michael J, Amin Agita, Pentecost Brian T, Yang Yi, Gierthy John F

Abstract excerpt

MCF-7 breast tumor cells form multicellular nodules (foci) over a confluent monolayer in an estradiol (E2)-dependent, antiestrogen-sensitive reaction. A cell line cloned from MCF-7 that displays these phenotypes was probed to determine the effects of long term exposure to tamoxifen on the growth of foci, estrogen receptor alpha (ERalpha) status, and gene responsiveness to E2. In one of two experiments, a...

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Source

Identifiers

PMID: 12943988
DOI: 10.1016/s0303-7207(03)00256-9

Genes

TMX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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