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Article

Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation.

International journal of cancer - 15 Jan 2006

Hiscox Stephen, Jiang Wen Go, Obermeier Kathrin, Taylor Kathryn, Morgan Liam, Burmi Raj, Barrow Denise, Nicholson Robert I

Abstract excerpt

We have previously demonstrated that, following acquisition of endocrine resistance, breast cancer cells display an altered growth rate together with increased aggressive behaviour in vitro. Since dysfunctional cell-cell adhesive interactions can promote an aggressive phenotype, we investigated the integrity of this protein complex in our breast cancer model of tamoxifen resistance. In culture,...

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Share to Antineoplastic Agents, Hormonal
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Drug Resistance, Neoplasm

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Source

Identifiers

PMID: 16080193
DOI: 10.1002/ijc.21355

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation.PMID 16080193Read ↗

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