Article
Characterization of tamoxifen stimulated MCF-7 tumor variants grown in athymic mice.
Breast cancer research and treatment - 1 Jan 1994
Wolf D M, Jordan V C
Abstract excerpt
The non-steroidal antiestrogen tamoxifen (TAM) is successfully used to treat all stages of breast cancer in both pre- and postmenopausal women. Unfortunately, most women treated with TAM eventually develop resistant tumor recurrences which require intervention with a second-line endocrine therapy...
Topics
- Animals
- Blotting, Western
- Breast Neoplasms
- Cell Division
- Cell Line
- Clone Cells
- Female
- Genetic Variation
- Humans
- Mice
- Mice, Nude
- Postmenopause
- Premenopause
- RNA, Messenger
- RNA, Neoplasm
- Receptors, Estrogen
- Receptors, Progesterone
- Tamoxifen