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Article

Altered expression of the IGF-1 receptor in a tamoxifen-resistant human breast cancer cell line

29 Jan 1999

Abstract excerpt

The relationship between oestrogen (E2) and insulin-like growth factor-one (IGF-1) was examined in both tamoxifen-sensitive (MCF 7/5-21) and tamoxifen-resistant (MCF 7/5-23) subclones of the MCF 7 cell line. Both subclones were grown in defined, serum-free (SF) medium over a period of 7 days with the addition of E2 or IGF-1 or a combination of both agents. Growth of both MCF 7/5-21 and 7/5-23 cells was stimulated...

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Share to Estrogen and related hormone effects
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Identifiers

PMID: 10070856
DOI: 10.1038/sj.bjc.6690112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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