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Article

Estrogen-stimulation of postconfluent cell accumulation and foci formation of human MCF-7 breast cancer cells.

Journal of cellular biochemistry - 1 Feb 1991

Gierthy J F, Lincoln D W, Roth K E, Bowser S S, Bennett J A, Bradley L, Dickerman H W

Abstract excerpt

Foci, nodules of cellular overgrowth, that appear after confluence are an in vitro characteristic of malignant transformation. A well-studied in vitro model of estrogen-dependent tumors is the MCF-7 cell line, derived from a pleural metastasis of a human breast adenocarcinoma. We report that cult...

Topics

Adenocarcinoma
Animals
Breast Neoplasms
Cattle
Cell Division
Contact Inhibition
Culture Media
Estradiol
Estrogens
Humans
Male
Mice
Mice, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Transplantation

Neoplasms, Hormone-Dependent

Phenotype

Piperidines

Raloxifene Hydrochloride

Source

Identifiers

PMID: 2055945
DOI: 10.1002/jcb.240450209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2055945-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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