Human disorders caused by the disruption of the regulation of excitatory neurotransmission.

Abstract excerpt

The nicotinic acetylcholine receptors (nAChRs) are members of the large family of ligand-gated ion channels, and are constituted by the assembly of five subunits arranged pseudosymmetrically around the central axis that forms a cation-selective ion pore. They are widely distributed in both the nervous system and non-neuronal tissues, and can be activated by endogenous agonists such as acetylcholine or exogenous...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Angelman Syndrome
• Share to Epilepsy, Frontal Lobe
• Share to Excitatory Postsynaptic Potentials