Article
Theoretical design of a gene therapy to prevent AIDS but not human immunodeficiency virus type 1 infection.
Journal of virology - 1 Sept 2003
Weinberger Leor S, Schaffer David V, Arkin Adam P
Abstract excerpt
Recent reports confirm that, due to the presence of long-lived, latently infected cell populations, eradication of human immunodeficiency virus type 1 (HIV-1) from infected patients by using antiretroviral drugs will be exceedingly difficult. An alternative to virus eradication may be to use gene therapy to induce a pseudo-latent state in virus-producing cells, thus transforming HIV-1 into a lifelong, but...
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