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Article

p300 is involved in formation of the TBP-TFIIA-containing basal transcription complex, TAC.

The EMBO journal - 1 Sept 2003

Mitsiou Dimitra J, Stunnenberg Hendrik G

Abstract excerpt

We have recently identified a novel basal transcription complex, TAC, that is present and active in embryonal carcinoma (EC) cells but not in other adult cells such as COS7. In the search for factors involved in TAC formation, we found that expression of the adenoviral 12S E1A oncoprotein abolishes TAC formation in EC cells. This effect of E1A depends on its N-terminal domain that is essential for cell...

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Source

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Identifiers

PMID: 12941701
DOI: 10.1093/emboj/cdg419
PMCID: PMC202362

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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