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Article

Activation of Integrated Provirus Requires Histone Acetyltransferase

1 Sept 1998

Abstract excerpt

A unique aspect of the retrovirus life cycle is the obligatory integration of the provirus into host cell chromosomes. Unlike viruses that do not integrate, retroviruses must conserve an ability to activate transcription from a chromatin context. Human immunodeficiency virus (HIV)-1 encodes an unusual and an unusually potent transcriptional transactivator, Tat, which binds to a nascent viral leader RNA, TAR. The...

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PMID: 9733796
DOI: 10.1074/jbc.273.38.24898

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Activation of Integrated Provirus Requires Histone AcetyltransferasePMID 9733796Read ↗

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Regulation of cellular gene expression and function by the human immunodeficiency virus type 1 tat proteinSemantic proximity Read ↗

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HIV-1 Tat: An update on transcriptional and non-transcriptional functionsSemantic proximity Read ↗

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