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Article

The transforming acidic coiled coil (TACC1) protein modulates the transcriptional activity of the nuclear receptors TR and RAR.

BMC molecular biology - 15 Jan 2010

Guyot Romain, Vincent Séverine, Bertin Julie, Samarut Jacques, Ravel-Chapuis Patrick

Abstract excerpt

BACKGROUND: The transcriptional activity of Nuclear hormone Receptors (NRs) is regulated by interaction with coactivator or corepressor proteins. Many of these cofactors have been shown to have a misregulated expression or to show a subcellular mislocalization in cancer cell lines or primary tumors. Therefore they can be factors involved in the process of oncogenesis. RESULTS: We describe a novel NR coregulator,...

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Source

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Identifiers

PMID: 20078863
DOI: 10.1186/1471-2199-11-3
PMCID: PMC2822774

Genes

TACC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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