Article
DNA damage modulates nucleolar interaction of the Werner protein with the AAA ATPase p97/VCP.
Molecular biology of the cell - 1 Oct 2003
Partridge Juneth Joaquin, Lopreiato Joseph Onofrio, Latterich Martin, Indig Fred Eliezer
Abstract excerpt
We report a novel nucleolar interaction between the AAA ATPase p97/VCP and the Werner protein (WRNp), a member of the RecQ helicase family. p97/VCP mediates several important cellular functions in eucaryotic cells, including membrane fusion of the endoplasmic reticulum and Golgi and ubiquitin-dep...
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