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Article

Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATP-dependent fashion.

Journal of structural biology - 1 Jan 2000

Indig Fred Eliezer, Partridge Juneth Joaquin, von Kobbe Cayetano, Aladjem Mirit I, Latterich Martin, Bohr Vilhelm A

Abstract excerpt

We have previously shown that the Werner syndrome helicase, WRNp, a member of the RecQ helicase family, forms a tight molecular complex with the p97/Valosin containing protein (VCP), a member of the AAA (ATPases associated with diverse cellular activities) family of proteins. This interaction is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15037256
DOI: 10.1016/j.jsb.2003.11.009

Genes

VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15037256-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATP-dependent fashion.PMID 15037256Read ↗

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Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome proteinSemantic proximity Read ↗

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