Article
The neuropathology of the trisomy 16 mouse.
Critical reviews in neurobiology - 1 Jan 1994
Lacey-Casem M L, Oster-Granite M L
Abstract excerpt
The purpose of this review is to describe the neuropathology of mouse trisomy 16 and to compare that pathology with the pathologic features observed in individuals with Down syndrome (DS) trisomy 21 (Ts21). Additionally, we will compare the neuroanatomic, neurochemical, and neurophysiologic abnormalities observed in both DS and in mouse trisomy 16 (Ts16). We discuss strategies that have been used to circumvent...
Topics
- Animals
- Brain
- Chimera
- Down Syndrome
- Humans
- Mice
- Mice, Transgenic
- Phenotype
- Trisomy