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Article

Different domains of synaptotagmin control the choice between kiss-and-run and full fusion.

Nature - 21 Aug 2003

Wang Chih-Tien, Lu Juu-Chin, Bai Jihong, Chang Payne Y, Martin Thomas F J, Chapman Edwin R, Jackson Meyer B

Abstract excerpt

Exocytosis-the release of the contents of a vesicle--proceeds by two mechanisms. Full fusion occurs when the vesicle and plasma membranes merge. Alternatively, in what is termed kiss-and-run, vesicles can release transmitter during transient contacts with the plasma membrane. Little is known at the molecular level about how the choice between these two pathways is regulated. Here we report amperometric recordings...

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Source

Identifiers

PMID: 12931189
DOI: 10.1038/nature01857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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