Information perspectives of the Haseman-Elston method.

Abstract excerpt

The Haseman-Elston regression approach can be viewed as a special case in a larger framework in which independent sibling pairs are ascertained, perhaps based on their phenotypes. Using likelihood arguments in an idealized setting, expressions are obtained for the inherent linkage information contained in the phenotype distributions. The results provide insight and analytic results that apply to general phenotype...

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