Article
Score test for detecting linkage to quantitative traits.
Genetic epidemiology - 1 Apr 2002
Putter H, Sandkuijl L A, van Houwelingen J C
Abstract excerpt
The two most popular methods to detect linkage of a quantitative trait to a marker are the Haseman-Elston regression method and the variance components likelihood-ratio test. In the literature, these methods are frequently compared and the relative advantages and disadvantages of each method are well known. In this article, we derive a score test for the variance component attributable to a specific quantitative...
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