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Article

IFN-gamma-producing gamma delta T cells help control murine West Nile virus infection.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2003

Wang Tian, Scully Eileen, Yin Zhinan, Kim Jung H, Wang Sha, Yan Jun, Mamula Mark, Anderson John F, Craft Joe, Fikrig Erol

Abstract excerpt

West Nile (WN) virus causes fatal meningoencephalitis in laboratory mice, thereby partially mimicking human disease. Using this model, we have demonstrated that mice deficient in gammadelta T cells are more susceptible to WN virus infection. TCRdelta(-/-) mice have elevated viral loads and greate...

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Source

Identifiers

PMID: 12928402
DOI: 10.4049/jimmunol.171.5.2524

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12928402-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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