Article
Most IL-4-producing gamma delta thymocytes of adult mice originate from fetal precursors.
Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2003
Grigoriadou Kalliopi, Boucontet Laurent, Pereira Pablo
Abstract excerpt
Thy-1(dull) gammadelta T cells constitute a distinct adult gammadelta T cell subset characterized by the expression of a TCR composed of Vgamma1Cgamma4 and Vdelta6Cdelta chains with limited junctional sequence diversity. However, several features of the expressed Thy-1(dull) TCR-gammadelta genes, in particular the absence or minimal presence of N region diversity and the almost invariable Ddelta2-Jdelta1...
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