Article
Molecular characteristics of human immunodeficiency virus type 1 subtype C viruses from KwaZulu-Natal, South Africa: implications for vaccine and antiretroviral control strategies.
Journal of virology - 1 Feb 2003
Gordon M, De Oliveira T, Bishop K, Coovadia H M, Madurai L, Engelbrecht S, Janse van Rensburg E, Mosam A, Smith A, Cassol S
Abstract excerpt
The KwaZulu-Natal region of South Africa is experiencing an explosive outbreak of human immunodeficiency virus type 1 (HIV-1) subtype C infections. Understanding the genetic diversity of C viruses and the biological consequences of this diversity is important for the design of effective control strategies. We analyzed the protease gene, the first 935 nucleotides of reverse transcriptase, and the C2V5 envelope...
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