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Article

Molecular motions of the outer ring of charge of the sodium channel: do they couple to slow inactivation?

The Journal of general physiology - 1 Sept 2003

Xiong Wei, Li Ronald A, Tian Yanli, Tomaselli Gordon F

Abstract excerpt

In contrast to fast inactivation, the molecular basis of sodium (Na) channel slow inactivation is poorly understood. It has been suggested that structural rearrangements in the outer pore mediate slow inactivation of Na channels similar to C-type inactivation in potassium (K) channels. We probed...

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Identifiers

PMID: 12913092
DOI: 10.1085/jgp.200308881
PMCID: PMC2234489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12913092-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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