Article
Transcriptional regulation of post-aggregation genes in Dictyostelium by a feed-forward loop involving GBF and LagC.
Developmental biology - 15 Feb 2006
Iranfar Negin, Fuller Danny, Loomis William F
Abstract excerpt
Expression profiles of developmental genes in Dictyostelium were determined on microarrays during development of wild type cells and mutant cells lacking either the DNA binding protein GBF or the signaling protein LagC. We found that the mutant strains developed in suspension with added cAMP expressed the pulse-induced and early adenylyl cyclase (ACA)-dependent genes, but not the later ACA-dependent,...
Topics
- Adenylyl Cyclases
- Amino Acid Motifs
- Animals
- Blotting, Northern
- Cell Adhesion
- Computational Biology
- DNA
- DNA, Complementary
- DNA-Binding Proteins
- Dictyostelium
- G-Box Binding Factors
- Gene Expression Profiling
- Gene Expression Regulation
- Gene Expression Regulation, Developmental