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Article

Aberrant growth and differentiation of oligodendrocyte progenitors in neurofibromatosis type 1 mutants.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 6 Aug 2003

Bennett Michael R, Rizvi Tilat A, Karyala Saikumar, McKinnon Randall D, Ratner Nancy

Abstract excerpt

Neurofibromatosis type 1 (NF1) patients are predisposed to learning disabilities, macrocephaly, and brain tumors as well as abnormalities on magnetic resonance imaging that are postulated to result from abnormal myelination. Here we show that Nf1+/- spinal cords in adult mice have more than twofold-increased numbers of NG2+ progenitor cells. Nf1-/- embryonic spinal cords have increased numbers of Olig2+...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12904481
PMCID: PMC6740670

Genes

FGF2
GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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