Article
Current states in understanding oligodendroglia-mediated neurological issues in neurofibromatosis type 1 (NF1).
Acta neuropathologica communications - 29 Sept 2025
Aghoghovwia Benjamin E, Shen Cheng-En, Bano Sabiha, Shyamala Nandini, Echeandia Marrero Alesandra, Irshad Khushboo, Sharafaldin Samer, Brossier Nicole M, Pan Yuan
Abstract excerpt
Neurofibromatosis type 1 (NF1) is among the most common neurogenetic disorders and is associated with an increased risk of developing tumors in the nervous system. Additionally, up to 80% of patients with NF1 experience neurological complications, including deficits in attention, memory, and executive function. Significant effort has been dedicated to studying how NF1 mutations autonomously dysregulate neuronal...
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