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Article

[Effect of 3' exonuclease activity of polymerase on extension of phosphorothioate-modified primers].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Aug 2003

Guo Zi-fen, Chen Lin-ling, Zhang Jia, Peng Cui-ying, Yang Xiang-dong, Zhang Xu, He Shu-ya, Liao Duan-fang, Li Kai

Abstract excerpt

OBJECTIVE: To determine whether 3'phosphorothioate-modified-2 terminal mismatched primers can turn off DNA polymerization mediated by Exo(+) polymerase. METHODS: Two-directional primer extension was performed using polymerase with and without 3' exonuclease activity. The effects of unmodified pri...

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PMID: 12903045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12903045-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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