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Article

Superb nucleotide discrimination by a novel on/off switch for DNA polymerization and its applications.

Molecular biotechnology - 1 Feb 2005

Li Kai, Zhang Jia, Chen Linling, Sommer Steve S

Abstract excerpt

With the use of polymerases having 3' to 5' exonuclease activity and 3' phosphorothioate-modified allele-specific primers, we recently devised a SNP-operated on/off switch controlling DNA polymerization. One advantage of this novel on/off switch is its adaptability to arrayed primer extension. To further expand its application in genetic analysis, this new on/off switch was evaluated in discrimination of the...

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Source

Identifiers

PMID: 15699566
DOI: 10.1385/MB:29:2:093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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