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Article

Divergence in patterns of invasion among subpopulations derived from a human carcinoma clone: roles of intercellular contacts and of cell-substratum adhesion.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 1992

Lang L M, Gailey C, Myrdal S E, Dedhar S, Auersperg N

Abstract excerpt

In tumor progression, populations of cancer cells with different patterns of growth and invasion arise within the same tissue and within individual neoplasms. We tested the hypothesis that, even in histologically undifferentiated carcinomas, such diversity may be influenced by differentiation-dependent adhesive mechanisms. We used as prototypes two cell lines that originated in the same clone of a poorly...

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Identifiers

PMID: 1290033
DOI: 10.1159/000217788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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