Article
Divergence in patterns of invasion among subpopulations derived from a human carcinoma clone: roles of intercellular contacts and of cell-substratum adhesion.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 1992
Lang L M, Gailey C, Myrdal S E, Dedhar S, Auersperg N
Abstract excerpt
In tumor progression, populations of cancer cells with different patterns of growth and invasion arise within the same tissue and within individual neoplasms. We tested the hypothesis that, even in histologically undifferentiated carcinomas, such diversity may be influenced by differentiation-dep...
Topics
- Carcinoma
- Cell Adhesion
- Cell Communication
- Cell Division
- Clone Cells
- Diazooxonorleucine
- Extracellular Matrix
- Female
- Humans
- Integrins
- Intercellular Junctions
- Neoplasm Invasiveness
- Neoplastic Stem Cells
- Phenotype
- Tumor Cells, Cultured
- Uterine Cervical Neoplasms