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Article

Multiple phenotypic divergence of mammary adenocarcinoma cell clones. I. In vitro and in vivo properties.

Clinical & experimental metastasis - 1 Jan 2000

Welch D R, Krizman D B, Nicolson G L

Abstract excerpt

The properties of cell clones derived from locally growing and spontaneous metastases of 13762NF mammary adenocarcinoma change during in vitro growth. This has been termed phenotypic drift and is reproducible in independent experiments using different cryoprotected cell stocks. To determine whether phenotypic drift in 13762NF cell clones is the result of an en bloc shift in the properties of all tumor cells, or...

Topics

Adenocarcinoma
Animals
Cell Division
Clone Cells
Karyotyping
Lung Neoplasms
Mammary Neoplasms, Experimental
Neoplasm Metastasis
Phenotype
Ploidies
Rats

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PMID: 6543709
DOI: 10.1007/BF00135172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-6543709-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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