Deregulation of the CEACAM Expression Pattern Causes Undifferentiated Cell Growth in Human Lung Adenocarcinoma Cells

Abstract excerpt

CEACAM1, CEA/CEACAM5, and CEACAM6 are cell adhesion molecules (CAMs) of the carcinoembryonic antigen (CEA) family that have been shown to be deregulated in lung cancer and in up to 50% of all human cancers. However, little is known about the functional impact of these molecules on undifferentiated cell growth and tumor progression. Here we demonstrate that cell surface expression of CEACAM1 on confluent A549...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Chemical Synthesis and Analysis
• Share to Peptidase Inhibition and Analysis
• Share to Radiopharmaceutical Chemistry and Applications