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Article

From genotypes to phenotypes: classification of the tumour profiles for different variants of the cadherin adhesion pathway.

Physical biology - 1 Jun 2012

Ramis-Conde Ignacio, Drasdo Dirk

Abstract excerpt

The E-cadherin adhesive profile expressed by a tumour is a characterization of the intracellular and intercellular protein interactions that control cell-cell adhesion. Within the intracellular proteins that determine the tumour adhesive profile, Src and PI3 are two essentials to initiate the formation of the E-cadherin adhesion complex. On the other hand, Src has also the capability of disrupting the...

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PMID: 22683697
DOI: 10.1088/1478-3975/9/3/036008

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